The main purposes of renal biopsy in patients with systemic lupus erythematosus are to confirm the diagnosis of lupus nephritis, to assess disease activity and/or chronicity, guide therapeutic ...

Intestinal failure–associated liver disease (IFALD) is a major concern in the management of pediatric intestinal failure, representing a leading cause of ...

The research in Singh laboratory is broadly focused on the pathophysiology of iron in disorders of the brain and the eye. Current interests in the lab include: Iron cycling in the eye. Pathophysiology ...

Like all forms of cancer, lung canceris defined by uncontrolled cell division caused by loss of physiological tissue homeostasis and failure of apoptotic cell death mechanisms. Aberrant cell ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this 12-part journey through a disease state ...

Mitochondria are instrumental in maintaining human brain homeostasis, and disturbed mitochondria associate with neuronal dysfunction and related pathology in neurodegenerative diseases including ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their specific roles in the progression of disease remain unknown. To address this gap ...

Scientists have shown that a protein called membralin is critical for keeping Alzheimer's disease pathology in check. The study shows that membralin regulates the cell's machinery for producing ...

1 Vascular Immunology Unit, Department of Pathology, Sydney Medical School, The University of Sydney, Camperdown NSW 2042, Australia. Cerebral malaria (CM) is a complex of syndromes relating to the ...

What are the lasting effects of COVID-19 on the body? Paul Benson, M.D., Professor and Autopsy Section Head in the Department of Pathology's Division of Anatomic Pathology, was awarded a Researching ...

Emphysema refers to the irreversible damage caused to the delicate air sacs in the lungs called alveoli. The exact pathogenesis of emphysema has been an important subject of research, although the ...