Some forms of synaptic plasticity involve changes in the probability of presynaptic synaptic vesicle release, but the mechanisms remain poorly understood. In this study, Midorikawa and Sakaba suggest ...

The paper S.S.H. Wang et al., “Fusion competent synaptic vesicles persist upon active zone disruption and loss of vesicle docking,” Neuron, 91:777-91, 2016. Hair trigger Neurons send each other ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...

For decades, neuroscientists have debated whether synaptic vesicles “kiss-and-run” or do an irreversible “full collapse” when releasing neurotransmitters. Now, a team in China has frozen that moment ...

Vesicle recycling in the presynaptic terminal at one end of a neuron, showing the role of dynamin during the last step of endocytosis (membrane retrieval), where the protein cuts off the vesicle from ...

Your brain is responsible for controlling most of your body’s activities. Its information processing capabilities are what allow you to learn, and it is the central repository of your memories. But ...

Senior Scientist in Biological Systems at Oak Ridge National Laboratory, Joint Faculty Professor in Physics and Astronomy, University of Tennessee Charles Patrick Collier receives funding from the ...