Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of ...

Heterotrimeric G proteins, comprising Gα, Gβ and Gγ subunits, are central to the transduction of extracellular signals into precise intracellular responses in plants. These proteins not only regulate ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

In new research, scientists at the Department of Energy's SLAC National Accelerator Laboratory, in collaboration with ...

Peptide science has expanded rapidly in recent decades, revealing molecules with intriguing signaling roles that may influence diverse regenerative and organizational processes within an organism.

Scientists led by Sergey Troyanovsky, Ph.D., professor of Dermatology and of Cell and Developmental Biology, have uncovered new intracellular mechanisms promoting cell-cell adhesion, a process ...

A blast of winter air and a dollop of mint toothpaste shouldn’t have much in common. Yet, both trigger the exact same ...

In a demonstration that could help pave the way for gene therapies with fewer side effects, several human cell types have ...

Terahertz (THz) radiation is increasingly explored for biomedical applications, however, its non-thermal effects on cellular metabolism and regulatory networks remain insufficiently characterized.

A newly identified protein pair may drive brain cell death in Alzheimer’s, offering a clearer explanation of how the disease progresses.