The field of RNA-targeted therapeutics is rapidly evolving, offering groundbreaking opportunities for the treatment of a wide array of diseases ...

A research team from The Hong Kong University of Science and Technology (HKUST) has made an advance in understanding the molecular machinery of RNA silencing. The team uncovered how the human enzyme ...

A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the ...

A new study in Nature has mapped, at atomic resolution, how the enzyme DICER slices precursor microRNAs at exactly the right ...

RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste.

A new method can test the activity of thousands of RNA enzymes, called ribozymes, in a single experiment. The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA ...

Study reveals how an RNA enzyme drives the postnatal switch from glucose to fatty acids in heart cells, highlighting ketogenesis as essential for metabolism. Study: The tRNA methyltransferase Mettl1 ...

A metabolic enzyme studied for over seven decades has a hidden second function – it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as their use continues to grow, so does a fundamental challenge: producing RNA ...