Little is known about the effect of physical activity in early life on subsequent growth and regulation of inflammation. We previously reported that exposure of muscles in growing rats to IL-6 results ...

Ripples of nerve cell activity that lock in memories may have an unexpected job outside of the brain: Dropping blood sugar levels in the body. Just after a burst of ripples in a rat’s hippocampus, ...

R47H is a rare variant in TREM2 that triples the risk of Alzheimer’s disease in heterozygous carriers. This knock-in rat model carries the R47H mutation in the rat Trem2 gene and a humanized Aβ ...