This image shows a metastatic melanoma tumor in a lung. Blood vessels at the tumor site (yellow) express a protein called P-selectin. Blood vessels not expressing P-selectin are green. Nanoparticles ...

Selectins are required for the trafficking of innate immune system cells, T lymphocytes and platelets. The absence of selectins or their ligands has severe health consequences, with recurrent ...

Dynamics of growth of transplantable sarcoma 45 (S45) in injection of autologous and allogenic serum. Dynamics of IGF-I, IGF-II and TGF-β1 in lung and liver in the early stages of metastasis in ...

The up-regulation of P-selectin in endothelial cells and platelets contributes to the cell–cell interactions that are involved in the pathogenesis of vaso-occlusion and sickle cell–related pain crises ...

In a surprising discovery, a ‘sticky molecule’ that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new ...

An open-label expanded-access study to evaluate the safety, tolerability, and pharmacokinetics of trifluridine/tipiracil in patients with advanced solid tumors and hepatic impairment. This is an ASCO ...

When cancer metastasizes, cells break off from the primary tumor, travel through the lymphatic or circulatory system, and then invade other tissue. Now researchers have found a protein that allows ...

A Princeton-led team of researchers has discovered a factor that promotes the spread of cancers to bone, opening the way toward treatments that could mitigate cancer’s ability to colonize bone. The ...

It’s the first bond between a mother and her child–and arguably, the most vital one. When a newly created human embryo enters its mother’s uterus, it must attach to the wall if it’s going to continue ...