Antimicrobial resistance (AMR) poses a major global health challenge by compromising the effectiveness of current therapies for infectious diseases. While ...

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

This summer, over 50 researchers in the NSF EMBRIO Institute convened to share their newest findings on cellular signaling and organization that drives wound repair, cellular defense, and organismal ...

Sex differences in the prevalence, severity, and disability associated with pain are well documented in both clinical and preclinical research. Despite ...

In a major brain science breakthrough, New Orleans-based researchers and collaborators have discovered a nerve signaling mechanism that takes place outside the cell, flipping on a 'pain switch.' This ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

Acetylcholine "conductors" in the striatum directly trigger serotonin release, offering new insights into the origins of OCD ...

Drawing inspiration from natural cell signaling cascades, chemists at Université de Montréal (UdeM) have developed a DNA-based signaling cascade that allows them to quantify and report via an easily ...