To simulate trans-ethnic meta-analysis, we performed a GWAS meta-analysis for a given iteration across all ancestral populations using the inverse-variance method with the assumption of a fixed-effect ...

Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

Statistical significance is a critical concept in data analysis and research. In essence, it’s a measure that allows researchers to assess whether the results of an experiment or study are due to ...