为阐明SNAREopathies临床表型差异的分子根源,研究团队聚焦SNAP-25层+5位点I192T/N突变,结合单分子光镊、电生理与数学建模 ...
N-ethylmaleimide-sensitive factor (NSF) and α soluble NSF attachment proteins (α-SNAPs) work together within a 20S particle to disassemble and recycle the SNAP receptor (SNARE) complex after ...