一篇发表在2025年《Nature Genetics》上的重磅论文,题目为“Single-cell and spatial transcriptomics reveal mechanisms of radioresistance and immune ...
引言如果一个基因被敲掉后,肿瘤更容易转移,我们通常会问:这个基因调控了什么通路?但随之也出现了一个更难、也更接近真实生命过程的问题:这个基因是在组织里的哪个位置发挥作用?5月26日,《Cell》的研究报道“Uncovering spatially ...
A new study in Science Bulletin presents DVSTP, a deep learning system that integrates pathology images with spatial ...
Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...
Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...
Inflammatory bowel disease (IBD) is an umbrella term for Crohn's disease and ulcerative colitis, which both involve chronic inflammation ... | Cell And Molecular Biology ...
New AI-powered spatial transcriptomics tools are transforming cancer research by revealing how cells are organized and interact within tumors. These methods combine histology images, gene expression ...