Genes contain the essential building instructions for life, guiding cells on which amino acids to assemble in what sequence to produce specific proteins. The human genome codes for about 20,000 such ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 ...

In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists have recently identified the mechanism behind regulated splicing of large constitutive exons which ...

CSHL’s Krainer lab used a technique called live-cell fluorescence imaging to observe the DDX23 enzyme (above, in green) in action. Together with the critical regulator protein SRSF1, DDX23 helps set ...