Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and proliferate ...

SHANGHAI, March 17 (Xinhua) -- Chinese researchers have achieved a medical breakthrough by using endoderm stem cell-derived islet-like tissues (E-islet) to restore pancreatic islet function in ...

Ceramide buildup due to faulty transport triggers stress responses that lock cells into senescence, revealing a potential ...

Three days post viral infection CD8 T cells (red) re-arrest with antigen presenting cells (cyan), where they are supplied with IL-2 by CD4 T cells (yellow), which migrate in a stop and go pattern. The ...

A team has identified a previously unknown phase of the immune response. The results challenge long-standing assumptions about the process called 'T-cell priming'. These new insights have significant ...