A team of scientists from the University of Cologne's Institute of Biochemistry has made a decisive discovery about the molecular basis of synapse formation in the central nervous system. They studied ...

Representative cryo-electron microscopy image: a coloured image of the 3D structure of gephyrin, which was calculated from the data. A team of scientists from the University of Cologne’s Institute of ...

A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction and memory loss in Alzheimer’s disease. A tool, developed in the Tracy lab ...

Scientists have uncovered a surprisingly large reserve of “silent synapses” in the adult brain—unused neural connections that can be rapidly activated to store new memories.

A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction and memory loss in Alzheimer’s disease. A tool, developed in the Tracy lab ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...

An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The ...

What are the three modes of neurotransmission, and how do they differ in terms of temporal coupling with action potentials? There are three modes of neurotransmission: stimulation-dependent release ...

Learning lots of new information as a baby requires a pool of ready-to-go, immature connections between nerve cells to form memories quickly. Called silent synapses, these connections are inactive ...

The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...