Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing ...

SynGenSys applies computational design strategies to engineer synthetic promoters with predictable performance characteristics for therapeutic and manufacturing applications. Professor David James ...

Researchers have unveiled CREsted, a comprehensive software powerhouse. CREsted doesn’t just describe how DNA works; it allows scientists to design entirely new, synthetic enhancers—short DNA ...

MIT engineers developed a way to set gene expression levels at off, low, or high. Using skin cells, the researchers delivered a cocktail (labeled with a red fluorescent protein, top row) that boosts ...

A study published in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

However, to precisely design sophisticated genetic circuits, interference between biological parts must be minimized, and encoding density must be increased for efficient gene circuit integration.

A team led by University of Pittsburgh’s Graham Hatfull has developed a method to construct bacteriophages with entirely synthetic genetic material, allowing researchers to add and subtract genes at ...

A new study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. The model then predicts which ...

Researchers have found that certain bacteria carry a naturally occurring system, built from repurposed CRISPR components, ...