Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers discovered a protein that acts as a molecular switch driving cocaine addiction by altering gene activity in a brain reward circuit. The protein regulates calreticulin, which dampens neuron ...

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

If only a small fraction of what we know about sugar’s effects were known about any other food additive, that substance would be banned.” Pure, White and Deadly by John Yudkin.

As our understanding of the neurobiology of addiction evolves, so do opportunities to develop more precise, brain-based interventions for co-occurring disorders. In our free webinar, “Advancing ...

Health Affairs' Rob Lott interviews Nora Volkow, director of the National Institute on Drug Abuse (NIDA) at the National Institutes of Health, to discuss addiction as a brain disorder, treatments for ...

Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the thalamus (PVT) ...

Most narcotics addicts seem to benefit from Suboxone, regardless of their histories of opiate addiction. Suboxone is very safe and effective and is a revolutionary step in the treatment of narcotic ...