For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in ...

Our study progresses from the rational design of polyplex micelles to the mechanistic elucidation of mRNA degradation, revealing RNase infiltration—rather than carrier dissociation—as the principal ...

Double-stranded RNA (dsRNA) is a well-recognized byproduct of in vitro transcription that poses significant challenges for the use of synthetic mRNA in research and therapeutic applications. Even ...

Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...

AI-driven tumor immunity mapping could improve mRNA vaccine design, delivery, and personalization in oncology. Read more.

Subtle differences in an mRNA sequence enables a ribosome to produce more or less of a certain protein. A new AI model called RiboNN predicts which sequences will be most efficiently produced and ...

In recent years, mRNA technology enabled the rapid development of vaccines to fight COVID-19, saving millions of lives. That same mRNA-powered approach to medicine—in which synthetic mRNA is ...

We asked experts about how the technology works, its safety and its potential in medicine. By Nina Agrawal Health Secretary Robert F. Kennedy Jr. has repeatedly questioned the safety of mRNA vaccines ...