A phase 1/2 trial of a novel viral vector gene therapy in adults with type 1 diabetes is scheduled to begin this year.

Researchers said their discovery of nine 'core' genes central to the development of type 1 diabetes could unlock new immune system pathways for targeting by immunotherapies. A team from the University ...

Missing genes and sequencing read registration in single-cell RNA-seq experiments. Credit: Nature Methods (2023). DOI: 10.1038/s41592-023-02003-w In 2018, researchers in the Caltech laboratory of Yuki ...

Background Penetrance of breast cancer (BC) among women who carry pathogenic variants (PVs) in BRCA1 is incomplete, and the ...

Advances in human genetics have enabled the investigation of the genetic architecture underlying numerous complex traits. Many publicly available databases establish a binary relationship between ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

Some people have a greater genetic risk than others of developing type 2 diabetes. Now, more of these at-risk people are ...

An international study co-led by researchers from the University of Massachusetts Amherst and Helmholtz Munich in Germany has uncovered hundreds of genes and proteins likely to play a causal role in ...

Nature and nurture both determine how likely you are to develop a particular disease. Hiroshi Watanabe/DigitalVision via Getty Images Sitting in my doctor’s examination room, I was surprised when she ...