Exenatide (Ex-4), a glucagonlike peptide-1 (GLP-1) receptor agonist currently used in the management of type 2 diabetes, could effectively treat drug addiction, including cocaine dependence, new ...

New research suggests the weight-loss medications could be powerful tools in tackling substance use disorders.

25% of Americans (70 million people) admitted they use illicit drugs, according to the most recent National Survey on Drug Use. 48.7 million people nationwide struggle with substance abuse according ...

Dr. Nora Volkow, who leads the National Institutes of Drug Abuse, would like the public to know things are getting better. Mostly. By Matt Richtel Historically speaking, it’s not a bad time to be the ...

Decades before it became known as "gas station heroin," tianeptine was prescribed to treat depression in dozens of countries. Now, U.S. poison control centers are reporting a dramatic spike in cases ...

Astrocytic GLUR5 and dopamine D1 signaling. Illustration showing that astrocytically expressed GLUR5 and dopamine D1R and their coupled Ca 2+ signaling triggers the release of astrocytic factors (e.g.

Ziyad Al-Aly receives funding from U.S. Department of Veterans Affairs. A patient of mine, a veteran who had tried to quit smoking for over a decade, told me that after he started a GLP-1 drug for his ...

On the perception that mental health patients caused by drug abuse no longer crave or remember the substances, she said this is not necessarily true. “Some patients continue using drugs even while ...