Donna L. Farber is a professor of surgical sciences, microbiology and immunology at Columbia University Irving Medical Center in New York City, New York, USA. Early in the pandemic, my team spotted ...

Gene expression reveals that different types of human cell can work as a unit. These cellular modules, found in several tissues, change during disease. However, suitable computational methods are ...

AN ADULT HUMAN body consists of some 37trn cells. Not so long ago, these were thought to come in 220 different types. That number, the product of painstaking decades spent peering through microscopes ...

Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need ...

What gets hyped, and what remains neglected, often depends on good storytelling. When the Human Genome Project began, in 1990, it had a simple story, well told. From a standing start, American ...

A new study answers the question of whether or not blood cell telomere length is a suitable proxy for telomere length in other tissues by examining over 20 human tissue types, finding variations and ...

Weill Cornell Medicine researchers have developed a computational method to map the architecture of human tissues in unprecedented detail. Their approach promises to accelerate studies on organ-scale ...

The first systematic study of its kind describes how human viruses including SARS-CoV-2 are better adapted to infecting certain types of tissues based on their ability to hijack cellular machinery and ...

An avalanche is caused by a chain reaction of events. A vibration or a change in terrain can have a cascading and devastating impact. A similar process may happen when living tissues are subject to ...

Microscopic images of human tissue are a cornerstone of biomedical research and clinical diagnostics. Yet despite their importance, these images often remain difficult to analyze systematically and to ...