这篇综述揭示了泛素D（UBD）通过调控糖酵解代谢重编程（Warburg效应）促进M2型巨噬细胞极化，从而增强卵巢癌（OC）免疫治疗抵抗（ITR）的关键机制。研究结合多组学分析和体内外实验证实，UBD通过上调LDHA、ALDOA等糖酵解关键酶表达，驱动免疫抑制性肿瘤微环境 ...

中新网上海3月14日电 (陈静 杨静)单孔双通道双介质(UBD)脊柱内镜技术由中国医学专家团队历经十年研发创新实践而成，是一项全新的脊柱内镜理念和技术。 记者14日获悉，这项中国原创医疗技术不断走向世界。继2024年日本爱知脊柱外科医院成立全球首家海外UBD ...

东方网记者刘轶琳10月17日报道:10月16日至18日，第一届UBD脊柱内镜及脊柱微创新技术国际大会在上海成功举办，来自中国、日本、印尼、泰国、越南、印度、新加坡、俄罗斯、厄瓜多尔等国家近100名海内外专家齐聚上海市东方医院，共同探讨单孔双通道双介质 ...

日前，上海市第十人民医院骨科贺石生教授与赵颖川教授受邀前往泰国曼谷，参加由泰国三军总医院与泰国脊柱微创学院联合举办的国际单孔双通道双介质（UBD）脊柱内镜技术会议及操作培训班。这是继2024年日本爱知脊柱外科医院成立全球首家海外UBD培训中心后 ...

中新网上海8月29日电 (陈静 顾莹)一位来自海南省的43岁男性持续4个月腰腿疼痛、行走困难，被多家医院医生确诊罹患“高位腰椎间盘突出钙化伴严重椎管狭窄”。一方面“大切口、椎板切除”的传统手术难度极大，风险很高、出血多且容易感染；另一方面，患者 ...

For immunostaining PE-, FITC-, APC-, and CyChrom-conjugated Abs against CD4 (RPA-T4), CD25 (M-A251), CD28 (CD28.2), TCRαβ (T10B9.1A-31), CTLA4 (BNI3), LGALS3 (B2C10 ...

To map T1D genes and their relation to environmental factors, we have used rat models of the disease. The LEW.1WR1 rat develops spontaneous diabetes at a low rate but is also very susceptible to the ...

If you want everything Ultra HD Blu-ray can deliver, but are on a tight budget, Samsung’s UBD-K8500 is the player to buy. Just be aware that you might have to tweak some settings to clear up the ...

This is a super-svelte Ultra HD Blu-ray player with a great interface and remote. Playback is excellent with the formats it supports. But we missed SACD playback and the player doesn’t support Dolby ...

Chris is the former Editor of Pocket-lint. He has been a technology journalist since 2008 and has covered the rise of Android and reviewed just about every important device along the way. Chris lives ...

The principles behind Understanding by Design (UBD) are not new. Backward planning, where teachers start with desired outcomes and plan lessons around them, reminds us of the psychologist Stephen ...