Explore the role of extracellular RNA in bacteria, communication, and its implications for medicine and disinfectant development.

引言微小RNA (microRNA, 简称miRNA) 常常扮演着关键的“基因沉默者”角色，它们如同巡航导弹，精准锁定靶向信使RNA (mRNA)，引导其走向降解的命运。然而，猎人偶尔也会沦为猎物。细胞内潜伏着一种被称为“触发”RNA ...

研究背景 RNA的5′端帽子结构在mRNA稳定性和翻译起始等基因表达调控中扮演着关键角色。长期以来，7-甲基鸟苷（m7G）被视为真核生物mRNA的经典帽子修饰。然而，近年的研究打破了这一固有认知：一系列细胞代谢物（如NAD+, dpCoA, FAD, ...

The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals danger. When the sun shines on your skin, what does it hit? When it causes a ...

The field of RNA-targeted therapeutics is rapidly evolving, offering groundbreaking opportunities for the treatment of a wide array of diseases ...

Oceans churned with lava. Air filled thick with smoke. Asteroids stormed down incessantly. Life during the Hadean Eon four billion years ago was a struggle, and yet that was when it began. 1,2 With no ...

The United States Food and Drug Administration has just approved the first-ever clinical trial that uses CRISPR-Cas13 RNA ...