Host–guest chemistry is a vibrant area of supramolecular science that explores the encapsulation of smaller guest molecules within the cavities of larger host compounds, leading to the formation of ...

For more than a century, the well-known 18-electron rule has guided the field of organometallic chemistry. Now, researchers at Okinawa Institute of Science and Technology (OIST), in collaboration with ...

Molecular structure of the new 20-electron ferrocene derivative, highlighting nitrogen (blue), iron (orange), hydrogen (green), and carbon (grey) atoms. Credit: Modified from Nature Communications ...

Scientists don’t know the limits of chemical space—the collection of all possible molecules—but a new analysis concludes chemists have discovered new compounds in that space at an exponential rate ...

Compound libraries are curated collections of chemical molecules used in drug discovery. A range of screening collections, ...

Matthew Addicoat receives funding from EPSRC and the Royal Society. The universe is flooded with billions of chemicals, each a tiny pinprick of potential. And we’ve only identified 1% of them.

Researchers from UC San Diego’s Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences have developed a new approach to scour the oceans for novel compounds that ...