(a) General diagram of the miRNA biogenesis pathway. (b) The major routes of cadmium exposure and its toxic impacts. AGO, Argonaute; Cd, cadmium; Exp5, Exportin 5; miRNA, microRNA; Ran/GTP, ...

Sequence motifs and cleavage site specificity of DCL1 and other RNase III enzymes. (a) The GHR motifs define the DCL1 cleavage site. (b) Sequence motifs recognized by DCL1, Dicer, and Drosha, with ...

4-Hydroxynonenal (4-HNE) is a major byproduct of lipid peroxidation, a process exacerbated by mitochondrial dysfunction and oxidative stress. Accumulation of 4-HNE protein adducts has been reported in ...

Groundbreaking research uncovers the role of miRNAs in driving cancer while offering innovative diagnostic tools and therapies, including solutions to chemotherapy resistance. Study: miRNA interplay: ...

MicroRNAs can make plants more capable of withstanding drought, salinity, pathogens and more. However, in a recent study scientists showed just how much we didn't know about the intricate processes ...