Determining and evaluating the affinity of small molecule binding to a therapeutic target is a major component of drug discovery and lead optimization. In a technical note entitled “Label-free ...

Light microscopes have revolutionized our understanding of the microcosmos, but their resolution is limited to about 100 nanometers. To see how molecules bond, break, or change their structure, we ...

Colloidal stability is calculated by balancing repulsive and attractive intermolecular interactions among protein molecules to sustain the native folded state. Less intermolecular interaction reduces ...