Toward the goal of elucidating endocrine system aging mechanisms, this study establishes the first single-cell aging atlas across multiple endocrine organs. The research reveals conserved aging ...

(A) The AlphaFold protein structure of GPER from the public database (https://alphafold.com/entry/Q99527). (B) E2, the GPER-specific agonist G1, SERMs, and SERDs ...

Hormones coordinate different body functions by carrying messages through the bloodstream to target cells and tissues. Hormonal imbalances occur through inadequate or excess hormone synthesis, which ...

Researchers have identified a specific hormone produced by pancreatic beta cells as a direct driver of obesity-linked ...

Researchers show that obesity alters pancreatic cells to produce cholecystokinin, which drives cancer growth, revealing new ...