In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that ...
New research from a multi-institutional team, published in Nature Cardiovascular Research, reveals that heart failure and atrial fibrillation share underlying genetic and molecular mechanisms, ...
A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...
Researchers at the Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, and the University of Utah School of Medicine, have demonstrated that a gene therapy can ...
The problem is that mammalian heart muscle cells, known as cardiomyocytes, lose their ability to proliferate shortly after birth. Researchers have long sought to induce these cells to start dividing ...
Cardiovascular disease continues to be the leading cause of death worldwide. But advances in heart-failure therapeutics have stalled, largely due to the difficulty of delivering treatments at the ...
A broken heart will mend over time. However, this isn’t the case for heart tissue following a heart attack. While skin and many other tissues of the body retain the ability to repair themselves after ...
University of Alabama at Birmingham researchers, led by Jianyi “Jay” Zhang, M.D., Ph.D., and Lei Ye, M.D., Ph.D., generated the human leukocyte antigen-knockout ...
A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...
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