Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of cellular signaling. This approach may enable precise control of disease-related ...

The GPCRact AI model goes beyond AlphaFold3 by predicting whether drugs functionally activate G-protein-coupled receptors ...

Targeted modulation of certain intracellular signaling proteins could represent an exciting new approach to drug development.

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth ...

A synthetic tripeptide inspired by snake venom is opening new investigative routes into cellular signalling and structural ...

Biopsies from people with persistent post-COVID-19 taste disturbance have revealed reduced expression of a key signalling ...

Skin, our largest organ, acts as a protective barrier against pathogens that try to invade our bodies while constantly ...