In a new study, researchers describe a method for pinpointing tumor-specific factors in blood that can elicit a protective immune response in the body and may one day be harnessed to produce an ...

Phase II trial on cisplatin-doxorubicin hydrochloride-paclitaxel (TAP) combination as neoadjuvant chemotherapy (NACT) for locally advanced cervical adenocarcinoma (LACA). This is an ASCO Meeting ...

In this paper we describe a reversion assay specific for the detection of -2 frameshift mutations occuring within short stretches of alternating GC sequences. We have compared a series of chemical ...

For more than a decade, scientist Stephen Albert Johnston and his team at Arizona State University's Biodesign Institute have pooled their energies into an often scoffed-at, high-risk, high-reward ...

Beijing Zhongke Journal Publising Co. Ltd. This study is led by Professor Kabin Xie (Institute of Huazhong Agricultural University College of Plant Science and Technology, Wuhan, China).

Clinical relevance of cyclin D1 protein overexpression in laryngeal squamous cell carcinoma. Kirsten ras (K-ras) point mutations are found in 30% to 56% of pulmonary adenocarcinomas by means of highly ...

SNIPRs (Single-Nucleotide-Specific Programmable Riboregulators) can identify any RNA sequence based on a single nucleotide difference. [Shireen Dooling, Biodesign Institute, ASU] SNIPRs, easy-to-build ...

Cystic fibrosis (CF) is an autosomal recessive disease due to a deleterious mutation in a chloride channel gene (CFTR = CF transmembrane conductance regulator), located on chromosome 7. From a ...

SAN DIEGO--(BUSINESS WIRE)--Turning Point Therapeutics, Inc., a clinical-stage precision oncology company designing and developing novel drugs to address treatment resistance, presented data from four ...

Identifying and classifying gene mutations - which are the permanent changes in a person's DNA genetic code - are critical in better understanding, and with research, eventually treating or preventing ...