Figure 2: Phenotype of K14-CAP1/Prss8 transgenic mice. Figure 3: Altered protein and lipid composition in K14-CAP1/Prss8 epidermis. To test the integrity of intercellular tight junctions in the ...
Domain Therapeutics SA has nominated PAR2 antagonist DT-9046 as a drug candidate with potential to treat various inflammatory diseases, including atopic dermatitis, inflammatory bowel disease and ...
Domain Therapeutics SA has disclosed proteinase-activated receptor 2 (PAR2; F2RL1) antagonists reported to be useful for the treatment of allergy, autoimmune and metabolic diseases, cardiovascular ...
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