The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

Selecting an RNA-seq workflow requires more than matching a kit to a sample type. Choices around ribodepletion, strandedness, and unique molecular identifiers (UMIs) directly influence data quality ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Morgan Hiebert (left) studies drug-resistant tuberculosis within the National Reference Centre for Mycobacteriology (Winnipeg, Manitoba) led by Hafid Soualhine, situated in the National Microbiology ...

A computational method called scSurv, developed by researchers at Institute of Science Tokyo, links individual cells to ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Bacteria aren’t just mindless microbes. Research by scientists at the Hebrew University of Jerusalem has revealed that single bacterial cells can carry a “memory” of their past environments—passing it ...

Researchers at Karolinska Institutet have developed a rapid and cost-efficient sequencing method that can identify antibiotic ...