编者按：2026年1月，美国西北大学医学院Ankit Bharat团队在《Med》杂志报道了一例颠覆性的临床案例——一名33岁患者在双肺全切后，依靠一套自主研发的“全人工肺”（Total Artificial Lung, TAL）系统存活48小时，并成功接受双肺移植，术后近三年生活质量正常。本文基于原始文献及《Nature》新闻深度解读，梳理其技术细节、生理学原理及临床意义，供同行参考。

PaO2/FiO2 Ratio and Ventilatory Ratio were measured 6, 12, 24, 48 and 72 hours after transition to APRV. Statistical analyses were performed using univariate repeated measures ANOVA and chi-squared ...

Overview of model parameters, constants, and outputs with their mathematical symbols, meaning, normal ranges, default values, and units. Normal ranges and default values were based on the in vivo ...

Introduction Endotracheal suction (ETS) is a frequent and necessary airway intervention for the intubated child. The aim of ETS is to clear the endotracheal tube and airways of respiratory secretions; ...

Background Venturi masks are commonly used in the hospital setting to deliver controlled percentages of oxygen. This is important for those at risk of hypercapnic respiratory failure and to accurately ...

Correspondence to Professor Siew C Ng, Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong; siewchienng{at}cuhk.edu.hk Objective Although COVID-19 is primarily a ...

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Introduction Automated systems for ventilator management to date have been either fully heuristic rule-based systems or based on a combination of simple physiological models and rules. These have been ...