circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...

Once considered cellular junk, non-coding RNAs are emerging as key players in everything from brain development to cancer — ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins—yet it exists in large quantities. A research team from ...

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

Researchers from the University of Ottawa’s Faculty of Science have achieved a significant breakthrough in the field of enzymology. Three graduate students, namely Noreen Ahmed, Nadine Ahmed, and ...

Long non-coding RNAs exist in the so-called "Wild West" (99%) of the human genome that is currently understudied. Not only does this finding have treatment implications for patients with ...

Researchers have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had ...

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that recognized ...

Scientists profiling small non-coding RNAs in postmortem brain tissue from people with schizophrenia and bipolar disorder have identified sweeping molecular disruptions that extend well beyond the ...