Peripheral nerve injury can result in potentially devastating neurological deficits and often disproportionately impacts young workers. Recovery of motor function after peripheral nerve injury ...

Cell membranes are dynamic structures that protect cells while constantly adapting to environmental change. For years, their behavior seemed to contradict basic physical laws linking structure and ...

For decades, neuroscientists have debated whether synaptic vesicles “kiss-and-run” or do an irreversible “full collapse” when releasing neurotransmitters. Now, a team in China has frozen that moment ...

Peukes et al. report compelling ultrastructures of excitatory synapses in the mouse forebrain that will serve as a reference for future work in the field. Their important findings using correlated ...

What are the three modes of neurotransmission, and how do they differ in terms of temporal coupling with action potentials? There are three modes of neurotransmission: stimulation-dependent release ...

Understanding brain function requires identifying the neuronal connections that underlie cognition behavior. We adapted trans-Tango, a powerful genetic strategy for anterograde circuit tracing in ...

Abstract: NEURON simulations for mossy fiber boutons show that conductivity changes in one bouton can induce resting membrane potential changes in nearby boutons, altering the pre-synaptic Calcium ...

ABSTRACT: Alzheimer’s disease (AD) is highly prevalent in the elderly population and leads to AD patients’ higher mortality, low life quality, and lead to a huge economic burden on the health system.

The replenishment of synaptic vesicles (SVs) to the active zone (AZ) at presynaptic terminals is required to sustain neurotransmitter release in response to high levels of neuronal activity. Despite ...

The black widow is one of the most feared spider species, and is widely associated with danger. This eight-legged marvel has earned its terrifying reputation through a venom that’s a potent cocktail ...